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Pharmacia was a pharmaceutical and biotechnology company in Sweden that merged with the United States pharmaceutical company Upjohn in 1995.
During World War II, Swedish chemist Björn Ingelman (who worked for Arne Tiselius at Uppsala university) researched various uses for the polysaccharide dextran. Together with the medical researcher Anders Grönwall, he discovered that dextran could be used as a replacement for blood plasma in blood transfusions, for which there could be a large need in wartime. Pharmacia, which then was still a small company, was contacted in 1943 and its CEO Elis Göth was very interested. The product Macrodex, a dextran solution, was launched four years later. Pharma-industri.se: Krig, socker och samarbete lade grunden till företag i världsklass ("War, sugar and cooperation laid the foundation for a world-class company"), accessed on June 17, 2009
Dextran-based products were to play a significant role in the further expansion of Pharmacia. In 1951, the company moved to Uppsala, Sweden, to get closer to the scientists with whom they cooperated, and Ingelman became its head of research. In 1959, Pharmacia pioneered gel filtration with its Sephadex products. These were also based on dextran and discoveries in Tiselius' department, this time by Jerker Porath and Per Flodin. In 1967 Pharmacia Fine Chemicals was established in Uppsala. In 1986 Pharmacia Fine Chemicals acquired LKB-produkter AB and changed its name to Pharmacia Biotech. Pharmacia Biotech expanded their role in the "biotech revolution" through its acquisition of PL Laboratories from Pabst Brewery offering a line of recombinant DNA specialty research chemicals. Sold to private interests in the 1990s, Pharmacia was first merged with "Kabi Vitrum" to form Kabi Pharmacia with headquarters in Uppsala. In 1993, Kabi Pharmacia bought Farmitalia, an Italian company that had developed doxorubicin, a chemotherapeutic.Staff. News: Farmitalia bought by Kabi Pharmacia . Ann Oncol (1993) 4 (5): 345.
In 1995 the company merged with the United States pharmaceutical company Upjohn, becoming known as Pharmacia & Upjohn and moved its headquarters to London.
In 1998, the company was divided into two business area. The pharmaceutical business became Pharmacia & Upjohn. The scientific instruments groups which sold chromatography resin, purification equipment, molecular biology reagents and electrophoresis products was purchased by Amersham plc in 1998 and was named Amersham Pharmacia Biotech. They later changed the name to Amersham Biosciences and ran their radiochemical and reagents business along with the highly profitable chromatography business. The Pharmacia Logo Drop remained as a highly recognized brand. Amersham Biosciences was sold to GE Healthcare in 2004 to become GE Healthcare Life Sciences. From 1 April 2020, GE Healthcare Life Sciences has been renamed Cytiva, following the sale of GE Healthcare Life Sciences from General Electric to Danaher Corporation in a $21.4 billion acquisition.
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